Cart
sales@molnova.com
NSC 625987
CAS No. 141992-47-4
NSC 625987 ( NSC 625987; NSC-625987; NSC625987; Cdk4 Inhibitor II )
Catalog No. M11755 CAS No. 141992-47-4
NSC 625987 is a potent, selective CDK4 inhibitor with IC50 of 0.2 uM, displays >500-fold selectivity over CDK2 (IC50 >100 uM for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 688 | Get Quote |
|
| 100MG | 1071 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNSC 625987
-
NoteResearch use only, not for human use.
-
Brief DescriptionNSC 625987 is a potent, selective CDK4 inhibitor with IC50 of 0.2 uM, displays >500-fold selectivity over CDK2 (IC50 >100 uM for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
-
DescriptionNSC 625987 is a potent, selective CDK4 inhibitor with IC50 of 0.2 uM, displays >500-fold selectivity over CDK2 (IC50 >100 uM for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
-
SynonymsNSC 625987; NSC-625987; NSC625987; Cdk4 Inhibitor II
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorCDK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number141992-47-4
-
Formula Weight271.33
-
Molecular FormulaC15H13NO2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESS=C1C2=C(C=CC=C2)NC3=C(OC)C=CC(OC)=C13
-
Chemical Name1,4-Dimethoxy-9(10H)-acridinethione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kubo A, et al. Clin Cancer Res. 1999 Dec;5(12):4279-86.
2. McInnes C, et al. Chem Biol. 2004 Apr;11(4):525-34.
3. Lang E, et al. Cell Physiol Biochem. 2015;37(3):1178-86.
2. McInnes C, et al. Chem Biol. 2004 Apr;11(4):525-34.
3. Lang E, et al. Cell Physiol Biochem. 2015;37(3):1178-86.
molnova catalog
related products
-
Lerociclib dihydroch...
Lerociclib dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3?and CDK4/CyclinD1, respectively.?
-
CDK4/6-IN-6
CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
-
CDK4/6-IN-2
CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor (IC50s: 2.7 and 16 nM) extracted from patent US20180000819A1 (Compound 1).
